New Highmark Stadium gets TNF debut: Bills vs. Lions NFL Week 2

The Buffalo Bills will play the first regular-season game at the new Highmark Stadium in NFL Week 2, hosting the Detroit Lions on Prime Video's Thursday Night Football for their home opener, the league announced. This preview announcement comes ahead of the full schedule release at 8 p. m.

ET on ESPN and NFL Network . HOUSEWARMING PARTY ON TNF ‼️ 📺 NFL Schedule Release 5/14 at 8pm ET on @nflnetwork @Ticketmaster | #GoBills pic. twitter.

com/c1ddzUVjT3 — Buffalo Bills (@BuffaloBills) May 11, 2026 For a franchise that had called their old building home since 1973, this is more than a ribbon-cutting. It's a primetime, national-audience launch of the next chapter for the team and its fans— and one that the league and front office mutually shared interest in showcasing on a global broadcast stage. Buffalo President of Football Operations and General Manager Brandon Beane has spent this offseason actively bolstering the roster around quarterback Josh Allen by way of free agency and the NFL Draft.

The Bills ' new home stadium will make its debut in a featured matchup against a competitive and physical NFC team as the TNF opener, complete with a National prime-time audience. Dan Campbell's Lions remain one of the NFC's more aggressive rosters in terms of playing style, along with a franchise quarterback in search of a Super Bowl championship as well. Like the Bills, the Lions restocked their roster with an eye on once again competing in the postseason.