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Guardians vs Cardinals Prediction, Picks & Odds for Today's MLB Game

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Two offenses that rarely strike out facing pitchers who don't miss bats mean a lot of runs in our Guardians vs. Cardinals predictions and MLB picks.

Want to get more Covers content? Add us as a preferred source on your Google account here . The Cleveland Guardians and St.

Louis Cardinals wrap up a three-game set this afternoon at Busch Stadium, with the first pitch scheduled for 1:15 p. m. ET.

With both lineups having success against today's starters, my Guardians vs. Cardinals predictions are eyeing the Over. Read more for my MLB picks for Wednesday, April 15.

Who will win Guardians vs Cardinals today: Cardinals moneyline (-110) The St. Louis Cardinals bounced back in Game 2 of this series, grabbing a 6-5 victory in extra innings after losing the opener. The Cardinals have now won four of their last five against the Cleveland Guardians , sweeping them last season.