Predicting the winner of every MLB game on Friday, April 10th, 2026
Winning in MLB on a daily basis is one of the toughest challenges in sports. With 162 games, constant lineup changes, pitching matchups, and the unpredictable nature of baseball, picking winners isn’t about guessing—it’s about analyzing matchups and picking up on patterns. Every day presents a new slate, new opportunities, and new value.
From analyzing starting pitchers and bullpen usage to identifying hot lineups and favorable matchups, success comes from staying consistent and trusting the process over the long haul. Here are today’s MLB predictions for final scores and the winners around the league. MORE: Ranking the 15 teams with the best chance to win the NBA Finals Pirates vs.
Cubs Aug 21, 2025; Chicago, Illinois, USA; Chicago Cubs starting pitcher Shota Imanaga (18) delivers a pitch against the Milwaukee Brewers during the first inning at Wrigley Field. Mandatory Credit: Kamil Krzaczynski-Imagn Images Pitching Matchup: Mlodzinski vs. Imanaga Score Prediction: 6-2 Winner: Cubs Diamondbacks vs.
Phillies Pitching Matchup: Soroka vs. Luzardo Score Prediction: 5-4 Winner: Phillies Marlins vs. Tigers Pitching Matchup: Paddack vs.
Montero Score Prediction: 4-2 Winner: Marlins Angels vs. Reds Pitching Matchup: Kochanowicz vs. Burns Score Prediction: 6-3 Winner: Reds Twins vs.