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March Madness Picks Against the Spread for Saturday, April 4

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JD Yonke sizes up both Final Four games from a spread standpoint, and is placing his faith in Illinois and Arizona to advance to the title game. Free March Madness ATS picks for Saturday, April 4.

Want to get more Covers content? Add us as a preferred source on your Google account here . The 2026 Men’s Final Four goes down tonight at Lucas Oil Stadium in Indianapolis.

The first matchup features the No. 3 Illinois Fighting Illini and the No. 2 UConn Huskies, followed by the heavyweight showdown of the No.

1 Michigan Wolverines and the No. 1 Arizona Wildcats. Read on for my March Madness picks against the spread for both Final Four games on April 4, and see why I have Illinois advancing to its second-ever National Championship Game.

March Madness against the spread picks on Saturday, April 4 Matchup Pick Illinois vs UConn -2 Arizona vs Michigan +1. 5 Lines courtesy of bet365. Cash your ML upset picks quickly with bet365's early win payout!