Duke vs LSU Prediction, Picks & Best Bets for Tonight's Women's March Madness Game
Our Duke vs. LSU predictions, odds & expert picks are calling for a tightly-contested battle in Sacramento on March 27, 2026.
Want to get more Covers content? Add us as a preferred source on your Google account here . There’s nothing quite like revenge, especially in the Sweet 16.
The Duke Blue Devils haven’t forgotten their 93-77 loss to the LSU Lady Tigers in December, a defeat that stung deeply. Since then, Duke has had time to regroup, make adjustments, and study how LSU executes its game plan. This sets the stage for a highly competitive matchup, with the Blue Devils ready to make tonight’s clash a closely contested battle.
Read on for my women's March Madness pick on how things will unfold on Friday, March 27. Duke vs LSU prediction Who will win Duke vs LSU? LSU: The Lady Tigers have been strong in the paint, both scoring and rebounding.
With standout post players controlling the boards, LSU can limit Duke’s second-chance points while generating extra opportunities for themselves. This physicality inside may force Duke to rely on perimeter shooting, which can be streaky. Duke vs LSU best bet: Duke +9.