St. John's vs Duke Predictions: Best Odds at Prediction Markets Like Kalshi

See why our analysts are backing the Blue Devils at Kalshi’s regulated event markets.

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1-seeded Duke Blue Devils against an upstart St. John's Red Storm team looking to continue its Cinderella run in what could be a dynamic Sweet 16 encounter Friday night. Thanks to the emergence of prediction markets like Kalshi, basketball fans in every state (aside from Nevada) can now invest in outcomes relating to Friday's St.

John's vs. Duke predictions . Read on for our advice on how to nail your NCAA basketball picks.