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Tennessee vs Iowa State Prediction, Picks & Odds for Friday's March Madness Game

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Our Tennessee vs. Iowa State predictions are calling for a rock fight in Chicago. Free March Madness picks for March 27.

Want to get more Covers content? Add us as a preferred source on your Google account here . Iowa State and Tennessee meet in the Sweet 16 with both teams trying to do the same thing to each other.

These are two of the best defenses left standing, and both are specifically built to destroy the other's highest-volume actions. My Tennessee vs. Iowa State predictions and March Madness picks break down why I expect a low-scoring matchup on Friday, March 27.

Tennessee vs Iowa State prediction Tennessee vs Iowa State best bet: Under 140. 5 (-116) Operating under the assumption that Josh Jefferson is unavailable, this Tennessee Volunteers defense is a nightmare for the Iowa State Cyclones . The two core tenants of the Cyclones offense are perimeter cutting actions and inside-out actions.

Both will get clamped, as the Vols defend them at a 98th percentile level . Iowa State’s defense smothers the things that Tennessee relies on the most in the halfcourt. Post-ups, which make up 20% of the Vols' offense, are defended by ISU at the 99th percentile .