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Tigers vs Padres Prediction, Odds & Home Run Pick for Today's MLB Game

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Our Tigers vs. Padres predictions and MLB picks for Thursday, March 26 see Tarik Skubal and Riley Greene powering Detroit to victory today.

Want to get more Covers content? Add us as a preferred source on your Google account here . All eyes will be on Tarik Skubal as he starts what could be his last year with the Detroit Tigers, and he’ll have the San Diego Padres in his sights in today’s season opener.

It’s a heavyweight pitching matchup at Petco Park as Skubal and Nick Pivetta square off, and my Tigers vs. Padres predictions expect Detroit’s ace to pave the way to a road victory. Take a closer look at this March 26 clash with my free MLB picks .

Tigers vs Padres predictions Tigers vs Padres best bet: Tigers moneyline (-134) After the Detroit Tigers ’ late-season collapse last year, it’s easy to forget their scorching 29-15 start. I see Detroit flying out of the traps again here. Tarik Skubal , coming off a 2.

21 ERA and 0. 89 WHIP in 2025 , should love the pitcher-friendly conditions at Petco Park. The visitors are 4-1 SU in their past five season openers , and their two-time Cy Young winner has shown that his stuff travels (2.