2026 NCAA tournament odds, picks, predictions: Best bets for Sweet 16 games

The 2026 NCAA tournament continues on Thursday and Friday with eight more exciting matchups, including potential Houston taking on an offensive powerhouse in Illinois and Rick Pitino's St. John's team facing No. 1 seed Duke.

The first rounds of March Madness saw plenty of favorites win — all 16 teams won on Friday for the first time since 1992 — but also its share of upsets (see: Iowa beating No. 1 Florida). What's in store for the Sweet 16?

Below you'll find the favorite wagers for all the games from our college basketball handicappers — Corbie Craig, Matt Jacob, Matt Russell and Frank Schwab. Draft your Yahoo Fantasy Baseball team for the 2026 MLB Season All odds courtesy of BetMGM . Best bets for Sweet 16 games No.

11 Texas vs. No. 2 Purdue (-6.