March Madness Odds 2026: Iowa Upsets Florida, Knocking Out a Tournament Favorite
Latest March Madness odds after Iowa shockingly sent top-seeded Florida home in the second round, while Duke, Arizona, and Michigan remain the clear favorites.
Want to get more Covers content? Add us as a preferred source on your Google account here . The first monster upset of the 2026 March Madness tournament took place in the second round of 32, as the No 9 seed in the South Region — Iowa — upset the No.
1 seed Florida 73-72 after Alvaro Folgueiras hit the go-ahead three with about four seconds remaining. Florida, which was the defending champion, became the first No. 1 (or No.
2) seed to fall in this year's tournament, leaving No. 1 seeds Michigan and Arizona as co-favorites on the March Madness odds board, followed by Duke (No. 1 seed in the East) and Houston (the highest remaining seed in the South).
Latest March Madness odds after Florida upset Team Next Opponent Michigan +310 Winner of Texas Tech/Alabama Arizona +310 No. 9 Utah State Duke +400 No. 5 St.