Siena vs Duke Predictions, Picks & Best Bets for Today's March Madness Game
•Yahoo Sports
The Blue Devils have what it takes to cover a monster spread, per our Siena vs. Duke predictions and March Madness picks for Thursday, March 19, 2026.
Want to get more Covers content? Add us as a preferred source on your Google account here . The No.
1 Duke Blue Devils are a massive 28. 5-point favorite against the No. 16 Siena Saints as they begin their NCAA Tournament today.
Tip-off is at 2:50 p. m. ET on CBS.
The only reason bookies aren’t making this spread steeper is the Blue Devils’ recent health concerns, but Duke’s bench is still loaded with top-tier talents, as my Siena vs. Duke predictions explain. Read on for my March Madness picks for Thursday, March 19.