Get Ready to Score Big with This Year's Sweet Ticket Chance!
Analyze 2026 South Region odds. From Florida's title defense to Houston's stifling defense, get expert picks and sleepers for this competitive region.
Want to get more Covers content? Add us as a preferred source on your Google account here . The Florida Gators are the defending NCAA national basketball champs, but a return visit to the Final Four could be a tough road.
The No. 1 team in the nation in 2025 has earned the top seed in the South Region, but the road to Indianapolis will likely require a meeting with either the Houston Cougars or the Illinois Fighting Illini โ both of whom are elite in their own right. Here's a breakdown of the South Region: Odds to win the South Region Team Covers' Take (1) Florida Gators +160 SECโs top-ranked high-octane offense (2) Houston Cougars +250 Nationโs most stifling interior defense (3) Illinois Fighting Illini +320 Elite scoring and veteran leadership (4) Nebraska Cornhuskers +1500 Sharpshooters thrive in transition game (5) Vanderbilt Commodores +1000 SEC tourneyโs hottest surprise team (6) North Carolina Tar Heels +6500 Explosive backcourt fuels deep run (7) Saint Mary's Gaels +4500 Disciplined play slows game down (8) Clemson Tigers +7500 Physicality dominates the paint area (9) Iowa Hawkeyes +4000 High-scoring unit pushes the pace (10) Texas A&M Aggies +10000 Relentless rebounding wins extra possessions (11) VCU Rams +15000 Aggressive pressure forces constant turnovers (12) McNeese Cowboys +40000 Upset-minded with elite defensive metrics (13) Troy Trojans +40000 Deep bench generates plenty of reserve energy (14) Penn Quakers +40000 Three-point skills could keep them close (15) Idaho Vandals +40000 Dangerous scorers with nothing to lose (16) Prairie View A&M Panthers +40000 Fast-paced attack could test favorites (16) Lehigh Mountain Hawks +40000 Balanced roster seeking historic upset Odds from bet365, one of our best betting apps .
Sign up with our bet365 promo code , or get one of our other sportsbook promos . South Region Favorite: Florida Gators Defending a national championship is extraordinarily difficult โ even if your elite starting frontcourt is returning. But Florida asserted itself well this season, finishing as the top rebounding team in the nation while boasting a Top 10 offense to get the nod as the South's top dog.
The Path: Florida will open its title defense against either Prairie View A&M or Lehigh, followed by a second-round date with the winner of the Clemson-Iowa tilt. The Concern: It's a small wonder Florida wound up with a No. 1 seed, and not just because of the seven losses: The Gators can't shoot free throws (234th nationally in FT%) or 3-pointers (327th in 3PT%).
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