Get Ready for the Unexpected: Top Seed Surprises in the 2026 East Regional March Madness!
By Jason Owens••Yahoo Sports
Will injuries and a difficult path through a murderer's row of NCAA coaching legends derail Duke's national title hopes?
With the 2026 NCAA men's tournament upon us, here's everything you need to know about the East region. [More regional breakdowns: West | Midwest | South ] Who are the favorites? No.
1 Duke ( +300 to win the national title at BetMGM ) No. 2 UConn (+2200) No. 4 Kansas (+4000) Duke is the No.
1 overall seed after a 32-2 campaign that featured a 17-1 record in ACC play and a win over fellow No. 1 seed Michigan on a neutral court. UConn had a shot at securing a No.
1 seed, but settled for a 2 seed after losing to St. John's in the Big East tournament championship. No.
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