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DURHAM, NORTH CAROLINA - JANUARY 10: Cameron Boozer #12 of the Duke Blue Devils reacts during the game against the SMU Mustangs at Cameron Indoor Stadium on January 10, 2026 in Durham, North Carolina. (Photo by Lance King/Getty Images) | Getty Images This has been one of the best seasons of men’s college basketball in the recent history of the sport, and it’s setting up for what should be an all-time great NCAA tournament. There are four powerhouse teams leading the field.

Can anyone knock off Duke, Florida, Michigan, and Arizona before the Final Four, or are we about to see all four No. 1 seeds win their regional for the second year in a row? There are worthy challengers all over the bracket, and anything can happen in a single elimination tournament.

Iowa State has never made the Final Four, but head coach T. J. Otzelberger might have his best team yet led by star senior forward Joshua Jefferson.

Houston came minutes away from a national championship last year, and now head coach Kelvin Sampson has multiple one-and-done draft picks on the roster in Kingston Flemings and Chris Cenac Jr. Illinois has the most efficient offense in the country with multiple 7-footers who fire away from three. Arkansas can score with anyone thanks to freshman star Darius Acuff.